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Fig. 3 | Molecular Medicine

Fig. 3

From: Role of Macrophage Migration Inhibitory Factor (MIF) in Peripheral Nerve Regeneration: Anti-MIF Antibody Induces Delay of Nerve Regeneration and the Apoptosis of Schwann Cells

Fig. 3

Effect of anti-MIF antibody with regard to apoptosis after nerve damage. Apoptosis was assessed based on the nuclei of cells undergoing characteristic DNA fragmentation, using TUNEL assays. From (a) to (d) at 4 week after surgery. Intratubal nerve segments in the control group (a) and the anti-MIF antibody-treated group (b). Distal nerve segments in the control (c) and the anti-MIF antibody-treated group (d). From (e) to (h) at 6 week after surgery. Intratubal nerve segments in the control (e) and the anti-MIF antibody-treated group (f). Distal nerve segments in the control (g) and the anti-MIF antibody-treated group (h). All magnifications are ×100.

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