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Fig. 4 | Molecular Medicine

Fig. 4

From: Part I: Pathogenetic Role of Peroxynitrite in the Development of Diabetes and Diabetic Vascular Complications: Studies With FP15, A Novel Potent Peroxynitrite Decomposition Catalyst

Fig. 4

Nitrotyrosine immunostaining in the multiple low-dose streptozotocin diabetes model in (A) the pancreas of a control (nondiabetic) mouse, (B) pancreas of a mouse at 14 days of diabetes, and (C) pancreas of an FP15-treated mouse at 14 days of diabetes. Note the marked increase in nitrotyrosine staining in the islets in diabetes, and its amelioration in the FP15-treated animals. Pictures representative of n = 4 to 5 experiments are shown. Original magnification: ×40.

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Molecular Medicine

ISSN: 1528-3658