Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: Part I: Pathogenetic Role of Peroxynitrite in the Development of Diabetes and Diabetic Vascular Complications: Studies With FP15, A Novel Potent Peroxynitrite Decomposition Catalyst

Fig. 5

Reversal of diabetes-induced endothelial dysfunction by FP15 in vascular rings from STZ-diabetic mice. Ach-induced endothelium-dependent relaxation is impaired in rings from diabetic mice, which is markedly improved by FP15 treatment. Each point of the curve represents the mean ± SEM of 5–7 pairs of experiments in vascular rings. *p < 0.05 in FP15 treated diabetic mice versus vehicle-treated diabetic mice.

Back to article page

Molecular Medicine

ISSN: 1528-3658