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Table 1 Reduction of tyrosine nitration by FP15 in vitro

From: Part I: Pathogenetic Role of Peroxynitrite in the Development of Diabetes and Diabetic Vascular Complications: Studies With FP15, A Novel Potent Peroxynitrite Decomposition Catalyst

 

0.1 M PBS, pH 7.4 (I = 0.26 M)

0.1 M PBS, 10 mM HCO3, pH 7.58, (I = 1.0 M)

No Catalyst

41.9%

55.1%

Exp. 1

4.9%

5.7%

Exp. 2

6.5%

5.6%

Exp. 3

5.0%

5.2%

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Molecular Medicine

ISSN: 1528-3658