Fig. 1From: The Role of the Complement Cascade in Ischemia/Reperfusion Injury: Implications for NeuroprotectionSchematic of cerebral infarct. Ischemic cerebral infarction is initiated by a thrombus lodged in the middle cerebral artery. This results in a central core of severely ischemic tissue surrounded by a poorly perfused area of tissue ischemia known as the penumbra.Back to article page