Table 2 Central nervous system production of complement components
From: The Role of the Complement Cascade in Ischemia/Reperfusion Injury: Implications for Neuroprotection
Cell Type | Complement Component |
|---|---|
Astrocyte | C1C9, factors B, D, H, I, C1INH, |
| Â | C4BP, DAF, MCP, CD59, clusterin, |
| Â | C3aR, C5aR, CR2 |
Microglia | C1, C1qB, C3, C4, clusterin, |
| Â | C1INH, CD59, CR1, CR3, CR4, |
| Â | C1qR, C3aR, C5aR |
Neuron | C1C9, factor B, CD59, DAF, C1INH, |
| Â | clusterin, CR1, C3aR, C5aR |
Oligodendrocyte | CD59, DAF, C3aR, C5aR |
Ependymal | C3, C5aR |
Endothelial | C1qB, C1r, C1s, C2, C3, C4, C5, |
| Â | C7, C8 gamma-subunit, C9 |