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Table 1 Genes included in Cluster 3

From: Gene Expression in Atherosclerotic Lesion of ApoE Deficient Mice

Gene Name

AC no.

10w C57B1/6

10w ApoE-/-

10w Ratio

20w C57B1/6

20w ApoE-/-

20w Ratio

Interleukin-7 receptor

M29697

6

16

2.63

24

9

0.36

Rac1 murine homolog

X57277

24

60

2.48

52

28

0.53

Transducin beta-2 subunit

U34960

30

64

2.15

41

22

0.55

Integrin alpha 5 (CD51)

U14135

19

39

2.05

19

17

0.89

Heat shock 60-kDa protein1 (HSP60); chaperonin; GroEL homolog

X53584

15

29

1.96

30

24

0.80

Golgi 4-transmembrane spanning transporter; MTP

U34259

93

182

1.95

253

135

0.53

Growth hormone receptor

M33324

28

53

1.88

24

16

0.65

Integrin alpha 4

X53176

18

33

1.83

15

12

0.80

Extracellular signal-regulated kinase 1 (ERK1); p44-MAPK; ERT2

M61177

55

99

1.81

78

50

0.64

VLA-3 alpha subunit

D13867

55

97

1.77

76

31

0.41

Ribosomal protein S29

L31609

37

65

1.76

60

48

0.80

CD31; platelet endothelial cell adhesion molecule 1

L06039

106

186

1.76

76

64

0.85

Fyn proto-oncogene;

U70324

10

17

1.71

19

16

0.80

Src family member

       

Rab-2 ras-related protein

X95403

113

192

1.70

324

244

0.75

CCHB3; calcium channel beta-3 subunit

U20372

29

49

1.70

26

26

1.00

APC (adenomatous polyposis coli protein)

M88127

14

23

1.68

19

16

0.80

Thrombomodulin

X14432

36

58

1.62

22

17

0.80

IFNgR2; interferon-gamma receptor second (beta) chain

S69336

14

23

1.61

60

54

0.89

Gem induced immediate early protein; Ras family member

U10551

14

23

1.61

24

12

0.51

Insulin receptor

J05149

43

68

1.59

15

16

1.03

SPI3; serpin

U25844

107

169

1.58

91

93

1.03

p58/GTA; galactosyl-transferase associated protein kinase

M58633

7

11

1.57

15

12

0.80

Fibroblast growth factor receptor basic (b FGF-R)

M28998

68

104

1.53

65

35

0.53

Mast cell factor

U44725

14

21

1.52

9

5

0.60

Phospholipase A2

D78647

141

214

1.52

145

119

0.82

Crk adaptor protein

S72408

40

60

1.49

39

38

0.98

Pre-platelet-derived growth factor receptor

X04367

73

108

1.48

67

48

0.72

Glucocorticoid receptor form A

X13358

55

82

1.48

80

69

0.86

Syp; SH-PTP2; adaptor protein tyrosine phosphatase

D84372

56

83

1.48

65

35

0.53

HSP27; heat shock 27-kDa protein 1

U03560

35

50

1.43

108

60

0.56

HMG-14 non histone chromosomal protein

X53476

222

315

1.42

371

264

0.71

Lamimin receptor 1

J02870

137

194

1.41

114

76

0.66

Cdk4; cyclin-dependent kinase 4

L01640

22

31

1.41

19

16

0.80

Androgen receptor

X53779

12

16

1.37

9

3

0.40

Macrophage cannabinoid receptor 2 (CB2)

U21681

4

5

1.37

6

3

0.53

Growth/differentiation factor 2 (GDF-2)

X77113

4

5

1.37

4

2

0.40