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Table 2 Genes included in Clusters 4 and 6

From: Gene Expression in Atherosclerotic Lesion of ApoE Deficient Mice

Gene Name

AC no.

10w C57B1/6

10w ApoE-/-

10w Ratio

20w C57B1/6

20w ApoE-/-

20w Ratio

CD18 antigen beta subunit; leukocyte adhesion LFA-1

X14951

11

29

2.68

4

59

13.59

Vascular cell adhesion protein 1

M84487

17

65

3.83

11

116

10.72

Nerve growth factor beta (beta-NGF)

K01759

9

18

2.05

2

21

9.60

C5A receptor

L05630

7

7

0.98

2

19

8.80

Cell surface glycoprotein MAC-1 alpha subunit

X07640

7

14

2.05

2

19

8.80

Macrophage inflamatory protein (MIP)

X12531

37

36

0.96

2

19

8.80

CD14 antigen

M34510

15

25

1.69

15

111

7.31

Hepatocyte growth factor; hepapoitein

X72307

9

14

1.52

2

16

7.20

Glutamate receptor channel subunit gamma

X04648

9

34

3.81

9

57

6.60

C-C chemokine receptor; monocyte chemo-attractant protein 1 receptor (MCP-IRA)

U56819

9

13

1.45

4

28

6.40

Interleukin-5 receptor

D90205

5

3

0.55

6

22

3.47

Corticotropin releasing factor receptor

X72305

5

4

0.82

2

7

3.20

Thrombopoietin

L34169

222

149

0.67

2

7

3.20

Gadd45; growth arrest and DNA-damage-inducible protein

L28177

26

19

0.74

6

16

2.40

Gut-specific Kruppel-like factor GKLF

U20344

19

21

1.08

6

16

2.40

Inducible nitric oxide synthase (iNOS)

M87039

15

10

0.64

4

10

2.40

Endothelin b receptor (Ednrb)

U32329

10

10

0.96

4

10

2.40

DNA-binding protein SMBP2

L10075

3

2

0.68

2

5

2.40

Glutamate receptor; ionotropic NMDA2A (epsilon 1)

D10217

14

8

0.54

2

5

2.40

Bone Morphogenetic protein 8a (BMP-8a)

M97017

11

10

0.87

2

5

2.40

Macrophage inflamatory protein 2 alpha (MIP2-alpha)

X53798

6

9

1.48

2

5

2.40

Interleukin 15

U14332

8

14

1.71

2

5

2.40

Ablphilin-1 (abi-1); similar to HOXD3

U17698

23

23

0.98

15

33

2.17

c-Fes proto-oncogene

X12616

12

10

0.87

13

28

2.13

Interferon alpha-beta receptor

M89641

8

7

0.86

6

14

2.13

Neuronal-cadherin (N-cadherin)

M31131

19

17

0.90

6

14

2.13

Keratinocyte growth factor FGF-7

Z22703

17

21

1.25

6

14

2.13

Nuclear factor related to P45 NF-E2

U20532

96

152

1.58

119

250

2.11

Clusterin; complement lysis inhibitor

L08235

275

379

1.38

305

615

2.02

PKC-beta; protein kinase C beta-II type

X53532

6

7

1.14

4

9

2.00

CD 40L receptor (TNF receptor family)

M83312

7

8

1.17

4

9

2.00

CD3 antigen delta polypeptide

M33158

8

8

1.03

4

9

2.00

Integrin alpha 2 (CD49b)

X75427

5

5

0.96

4

9

2.00

Glutathione peroxidase (plasma protein); selenoprotein

U13705

75

84

1.11

30

60

2.00

Insulin-like growth factor-IA

X04480

74

94

1.27

54

107

1.98

Bax; Bcl-2 heterodimerization partner and homolog

L22472

51

47

0.93

32

62

1.92

Ezrin; NF-2 (merlin) related filament/plasma membrane associated protein

X60671

9

11

1.22

13

24

1.87

SRY-box containing gene 4

X70298

40

25

0.62

9

16

1.80

Urokinase type plasminogen activator

X02389

15

16

1.10

9

16

1.80

FAF1; Fas-associated protein factor

U39643

151

129

0.86

11

19

1.76