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Table 3 Genes included in Cluster 5 and 7

From: Gene Expression in Atherosclerotic Lesion of ApoE Deficient Mice

Gene Name

AC no.

10w C57B1/6

10w ApoE-/-

10w Ratio

20w C57B1/6

20w ApoE-/-

20w Ratio

G-CSF receptor

M58288

5

7

1.37

2

12

5.60

Monotype chemoattractant protein 3

S71251

54

74

1.37

6

36

5.60

Nuk tyrosine-protein kinase receptor

L25890

14

10

0.73

2

10

4.80

Cellular retinoic acid binding protein II

M35523

5

10

2.05

4

21

4.80

Gamma interferon induced monokine

M34815

10

29

2.95

2

10

4.80

Cathepsin L

X06086

132

288

2.18

28

131

4.68

CD44 antigen

M27129

35

52

1.49

19

86

4.44

Vav proto-oncogene

X64361

23

24

1.04

4

19

4.40

Ung1; uracil-DNA glycosylase

X99018

17

7

0.40

4

19

4.40

P-selectin

X91144

42

35

0.83

4

19

4.40

Integrin alpha 6

X69902

8

15

1.88

4

19

4.40

Syk tyrosine-protein kinase

U25685

8

19

2.40

9

35

4.00

Ikaros DNA binding protein

L03547

7

10

1.47

2

9

4.00

c-Fms proto-oncogene

X68932

42

48

1.15

43

164

3.80

Cathepsin D

x53337

390

734

1.88

259

907

3.50

Intercellular adhesion molecule-1

X52264

13

20

1.53

4

14

3.20

Macrophage inflammatory protein 1 beta

M35590

3

4

1.37

2

7

3.20

Interleukin 1 beta

M15131

3

5

1.60

2

7

3.20

Cathepsin B

M14222

255

697

2.73

177

504

2.85

SLAP

U29056

1

6

6.16

2

5

2.40

Transforming growth factor beta

M13177

67

106

1.58

56

114

2.03

cAMP-dependent protein kinase type I-beta regulatory chain

M20473

4

7

1.71

4

9

2.00

Erf; Ets-related transcription factor

U58533

28

54

1.93

32

62

1.92

Pim-1 proto-oncogene

M13945

13

19

1.46

17

31

1.80

MDR1; P-glycoprotein

M14757

13

16

1.21

9

16

1.80

uPAR1 (CD87)

X62700

9

12

1.37

9

16

1.80

DP-1 (DRTF-polipeptide 1) cell cycle regulatory transcription factor

X72310

28

48

1.71

30

54

1.77

Kinesin-like protein KIF 3B

D26077

23

30

1.31

13

22

1.73

B7-2 (CD86); CD28 antigen antigen Iigand 2

L25606

8

11

1.37

11

17

1.60

CD28 (receptor for B71)

M34563

8

9

1.11

4

7

1.60

Platelet-derived growth factor (A chain)

M29464

19

23

1.19

13

21

1.60

Interleukin 6

X51975

14

18

1.27

6

10

1.60

Membrane-type matrix matalloproteinase

X83536

68

86

1.27

37

59

1.60

Interleukin-converting enzyme (ICE)

L28095

203

226

1.11

153

238

1.55

Elf-1 (Ets family transcription factor)

U19617

16

29

1.84

19

29

1.51

Cathepsin H

U06119

171

236

1.38

114

166

1.45

Fli-1 ets-related proto-oncogene

X59421

14

17

1.25

17

24

1.40

I-κB (I-kappa B) alpha chain

U36277

29

45

1.56

22

29

1.36

Insulin-like growth factor binding protein-4 (IGFBP-4)

X81582

67

101

1.50

164

218

1.33

CACCC Box-binding protein BKLF

U36340

33

38

1.16

69

90

1.30

Stat1

U06924

36

58

1.62

45

59

1.29

Interferon-inducible protein 1

U19119

13

23

1.79

28

36

1.29

Interferon-gamma receptor

M28233

11

15

1.37

11

14

1.28

Basic domain/leucine zipper transcription factor

L36435

4

7

1.71

15

19

1.26

GapIII; GTPase-activating protein

U20238

16

19

1.20

19

24

1.24

Beta-actin

M12481

721

1156

1.60

1443

1777

1.23

T-lymphocyte activated protein

M31042

65

85

1.31

41

50

1.22

MEK protein kinase

L02526

29

37

1.28

65

78

1.20

Transcription factor LRG-21

U19118

23

34

1.46

9

10

1.20

Interleukin-6 receptor beta chain

M83336

148

242

1.63

162

190

1.17

Glutathione S-transferase (microsomal)

J03752

49

70

1.43

37

41

1.13