Fig. 1

Photographs of bone marrow from alcoholics. In a sample of 138 consecutive patients undergoing bone marrow aspiration due to macrocytosis, 68 patients (49%) had a history of excessive alcohol consumption, 28 of whom were patients with severe ethanol dependence. Bone marrow aspirates from 12 alcoholic patients showed vacuolization of pronormoblasts (A,B). May-Grunwald-Giemsa stains of 69-year-old male alcoholic patient (A) and 39-year-old female patient with ethanol dependence (B) are shown.