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Fig. 3 | Molecular Medicine

Fig. 3

From: Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas

Fig. 3

Representative results of Ki-ras mutation (codon 12) analysis. M, 100 bp ladder; C, control PCR fragment before digestion (357 bps). Lanes 1, 2, 3, 5, and 6: BstNI restriction fragment length polymorphism (RFLP) results from tumor samples (cases 19, 20, 21, 23, and 24, respectively) without codon 12 mutations (305 bps). Lane 4: BstNI PCR RFLP results of case 22 harboring a codon 12 Ki-ras mutation (335 bps).

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