Fig. 5From: Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung CarcinomasIn a lung tumor cell, only one alteration (annotated. ) in the p53-p27-pRb network can be counterbalanced by the activity of the other network components (alternative pathways), whereas at least two alterations (annotated ) are required lor proliferation enhancement. See “Discussion” for details.Back to article page