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Table 2 Relationship between p27 expression, clinicopathologic parameters, pRb status, p53 status and Ki-ras mutations

From: Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas

  

Number

p27 Mean Value

p

Histology

AdCs

32

38.94 ± 13.21

0.001

 

SqCCs

30

27.47 ± 12.40

 

Ploidy

Aneuploid

39

28.33 ± 11.59

0.007

 

Diploid

24

37.50 ± 14.07

 

LN

Yes

36

31.75 ± 14.33

0.558

 

No

31

33.77 ± 13.67

 

Tumor stage

I

28

34.64 ± 14.04

 
 

II

21

33.76 ± 16.47

0.309

 

III

18

28.39 ± 9.86

 

pRb status

Aberrant

26

27.73 ± 13.05

0.02

 

Normal

41

35.83 ± 13.75

 

p53 status

Positive

39

28.97 ± 13.03

0.009

 

Negative

28

37.86 ± 13.78

 

Ki-ras mutations

Yes

14

34.71 ± 12.14

0.582

 

No

38

32.05 ± 16.36

 

p53pRb status

Normal

22

37.14 ± 13.01

 
 

1 alteration

25

35.80 ± 15.30

0.002

 

2 alterations

20

23.90 ± 8.79

 
  1. Abbreviations: AdCs, adenocarcinomas; SqCCs, squamous cell carcinomas.