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Table 5 Association between alterations in the p27-p53-pRb network, tumor kinetics, and ploidy

From: Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas

 

PI

 

AI

 

GI

 

Ploidy

Alter.

N Mean value p

 

N Mean value p

 

N Mean value p

 

Aneup. Dip. p

0

12 26.47 ± 7.55

 

11 0.31 ± 0.29

 

11 1.09 ± 0.32

 

6

6

1

21 29.41 ± 9.99

 

18 0.13 ± 0.47

 

17 1.34 ± 0.49

 

7

13

  

<0.0001

 

0.214

 

<0.05

 

0.002

2

13 39.13 ± 7.73

 

13 0.18 ± 0.33

 

12 1.38 ± 0.35

 

9

4

3

17 43.18 ± 9.86

 

17 0.02 ± 0.30

 

17 1.61 ± 0.34

 

17

1

  1. Abbreviations: N; number of samples; PI, proliferation index; AI, apoptotic index; GI, growth index; Alter., alterations; Aneup., aneuploidy; Dip., diploidy.
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Molecular Medicine

ISSN: 1528-3658