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Fig. 1 | Molecular Medicine

Fig. 1

From: An Antigenic Threshold for Maintaining Human Immunodeficiency Virus Type 1-specific Cytotoxic T Lymphocytes

Fig. 1

CTLp frequency and viral load in long-term nonprogressors (LNTPs). (A) Cytotoxic T lymphocyte precursor (CTLp) frequency in each subject was determined using limiting-dilution analysis (LDA). Effector cells were peripheral blood mononuclear cell (PBMC) cultured under standard LDA conditions. Target cells were autologous B lymphoblastoid cell lines (BLCL) that had been infected with either control vaccinia (open diamond) or recombinant vaccinia expressing human immunodeficiency virus (HIV) antigens: vAbT 299 (IIIBenv-gp160; open circle), vAbT 141 (IIIBgag-p55; open square), and vAbT 204 (IIIBpol; open triangle). (B) The corresponding viremia levels were measured using an reverse transcription polymerase chain reaction (RT-PCR) assay.

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Molecular Medicine

ISSN: 1528-3658