Fig. 1From: Expression and Characterization of Six Mutations in the Protoporphyrinogen oxidase gene among Finnish Variegate Porphyria PatientsA–F. Pedigrees of six VP families with novel mutations in the PPOX gene. Closed circle and square = affected female and male with clinically symptomatic disease; Open circle and square = unaffected family member; half-filled circle = asymptomatic individual carrying the affected gene; M+ = mutation positive; M− = mutation negative.Back to article page