Fig. 5From: Expression and Characterization of Six Mutations in the Protoporphyrinogen oxidase gene among Finnish Variegate Porphyria PatientsSchematic representation of the consequences of mutations affecting splicing and protein translation. Above exon/intron structure of human PPOX gene; solid and open boxes represent protein-coding and untranslated regions. Below the cDNA and protein translation are shown for each mutation; solid bars represent normally translated amino acids and open bars represent nonsense amino acids.Back to article page