Fig. 2
From: Transcriptional Regulation of the Human iNOS Gene by IL-1β in Endothelial Cells
Role of the NF-κB element at position −115 to −106 bp in the transcriptional activity of the human iNOS promoter in PVEC. The wild-type construct, phiNOS-1034Luc, is defined in Figure 1. The mutant construct, phiNOS-1034ANFκBLuc, features complete deletion of the NF-κB element at position −115 to −106 bp. Luciferase activity is expressed and normalized as in Figure 1. Values shown are the means ± SEM of five independent experiments.