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Fig. 2 | Molecular Medicine

Fig. 2

From: Pulmonary Inflammation Induced by a Recombinant Brugia malayi γ-glutamyl transpeptidase Homolog: Involvement of Humoral Autoimmune Responses

Fig. 2

Time course and intensity of serum total IgE (A), and B. malayi γ-GT-specific IgE (B) antibody responses to recombinant filarial in γ-GT-immunized mice. Sera from mice (n = 4) were pre-adsorbed overnight to protein G sepharose to remove blocking IgG before the measurement of total IgE and γ-GT-specific IgE by ELISA as described in Materials and Methods. Values are expressed as geometric mean ± SD, γ-GT-challenged mice, γ-GT/AL, or saline-challenged. * p = 0.021 significantly different values between γ-GT, and p = 0.034 between γ-GT/AL and control group (CL), respectively.

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