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Fig. 7 | Molecular Medicine

Fig. 7

From: Pulmonary Inflammation Induced by a Recombinant Brugia malayi γ-glutamyl transpeptidase Homolog: Involvement of Humoral Autoimmune Responses

Fig. 7

Lung immunohistochemistry using antibodies from B. malayi γ-GT-immunized mice showing specific autoimmune responses to endogenous murine γ-GT on airway epithelial cells from the bronchi. Lung sections with bronchi (b) from normal mice were incubated overnight at 37°C either with control serum A and B or with affinity-purified anti-B. malayi γ-GT antibodies (C and D). Panels C and D reveal the presence of autoimmune reactions (black) against the endogenous enzyme detected mainly on the airway epithelium (arrows). These reactions were absent from the sera of control animals (A and B). Original magnification A and C ×620; B and D ×840.

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Molecular Medicine

ISSN: 1528-3658