Skip to main content
Fig. 8 | Molecular Medicine

Fig. 8

From: Pulmonary Inflammation Induced by a Recombinant Brugia malayi γ-glutamyl transpeptidase Homolog: Involvement of Humoral Autoimmune Responses

Fig. 8

Autoantibodies against lung murine γ-GT in sera from mice immunized with B. malayi γ-GT. Western blot analysis of enzymatically-active murine γ-GT isolated from a nondenaturing gel. Lane 1 shows the immunoblot with control pre-immune serum. Lane 2, immunoblot analysis using affinity purified sera from B. malayi γ-GT immunized mice demonstrating autoantibodies against the 55 kDa murine heavy chain band, and a weaker ~150 kDa polypeptide representing possible membrane-bound enzyme. No such bands were detected in the controls.

Back to article page

Molecular Medicine

ISSN: 1528-3658