Fig. 6From: Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrityEthyl pyruvate does not inhibit NLRP3 agonists-induced mtROS production. MtROS levels were determined by MitoSOX staining of LPS-primed human acute monocytic leukemia cell lines (THP-1) after stimulation with ATP (5 mM) or nigericin (10 μM) in the presence or the absence of 5 mM EPBack to article page