Fig. 1
From: Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine
STA improved Hcy-impaired vascular relaxation. After pre-treatment of TA (a), MA (c) and RA (e) rings with STA (10 μM, 12 h), the arterial rings were exposed to Hcy (500 μM, 60 min). The cumulative concentration-response curves for ACh-induced relaxations of the phenylephrine-pre-contracted arterial rings were shown. b, d and f Representative traces of endothelium-dependent relaxations as in (a, c and e). Data were shown as mean ± SEM; n = 5 for each group, *P < 0.05 vs. Vehicle; #P < 0.05 vs. Hcy