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Fig. 5 | Molecular Medicine

Fig. 5

From: Overexpression of miR-21-5p promotes proliferation and invasion of colon adenocarcinoma cells through targeting CHL1

Fig. 5

MiR-21-5p promoted the invasion of COAD cells. a, b Cell number in miR-21-5p mimics group was more than that in NC mimics group, while that in miR-21-5p inhibitor group was less than that in NC inhibitor group detected by transwell assay. The scale bar was 50 μm. c, d The expressions of invasiveness-related factor MMP-2 and MMP-9 in miR-21-5p mimics group were higher than that in NC mimics group, while those in miR-21-5p inhibitor group were lower than that in NC inhibitor group detected by ELISA. **P < 0.01, compared with NC mimics group, ##P < 0.01, compared with NC inhibitor group

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