Fig. 4

Myocardial infarct sizes in wild type and α-MHC-HDAC4 mice in response to I/R injury. a Myocardial infarction in wild type littermates and α-MHC-HDAC4 mice. b Representative image of infarct size. At the end of the experimental protocol as described in Methods, the hearts were sliced into 4–5 sections and stained with 2,3,5-triphenyltetrazolium chloride followed by fixation in formalin. Viable areas are stained brick red, whereas infarcted areas are gray or white. Values represent mean ± SE (n = 5/per group). *p < 0.05 vs wild-type mice ^#p < 0.05 vs wild-type mice + TSA and α-MHC-HDAC4 mice