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Fig. 6 | Molecular Medicine

Fig. 6

From: Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury

Fig. 6

Active HDAC4 increased active caspase 3 and autophagy and decreased SOD1. a Western blot showing increased active caspase-3, decreased SOD-1, and increased LC-3I/II in the heart from HDAC4 transgenic mice; b Densitometric analysis of each protein level relative to wild type (n = 3 per group); Values represent mean ± SE, *p < 0.05 vs WT; #p < 0.05 vs WT + TSA. SOD: Superoxide dismutase; LC3: autophagosome associated lipidated isoform LC3

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