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Fig. 4 | Molecular Medicine

Fig. 4

From: Asymmetric expression of H19 and ADIPOQ in concave/convex paravertebral muscles is associated with severe adolescent idiopathic scoliosis

Fig. 4

Expression difference of H19 and ADIPOQ mRNA in paravertebral muscles of AIS patients is associated with curve severity and age at initiation. The relative expression difference of studied genes was calculated as the relative expression level of one gene in concave sided muscle minus that in convex sided. For (a), correlation analysis identified that the relative expression difference of H19 in AIS patients (n = 60) was positively correlated with the magnitude of spinal curve. For (b), the relative expression difference of ADIPOQ mRNA in AIS patients (n = 60) was negatively correlated with the magnitude of spinal curve. For (c), Heat map showed significant correlation of the expression difference of H19 and ADIPOQ mRNA in AIS patients (n = 60) with age at initiation of AIS

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