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Fig. 8 | Molecular Medicine

Fig. 8

From: The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9

Fig. 8

Effects of SOX9 on proliferation, invasion and migration of colorectal cancer cells a and b the cell proliferation of colorectal cancer cell lines DLD-1 and HT-29 transfected with different interference sequences, cell proliferation was the weakest in si-SOX9 group, and pcDNA3.1-SOX9 group had the strongest cell proliferation ability compared with NC group. The cell proliferation of si-SOX9 + miR-145 inhibitor group and NC group was comparative. c cell colony formation of colorectal cancer, the formation rate of colorectal cancer cells in the si-SOX9 group was remarkably slower than that of the NC group. The cell formation rate was significantly higher in pcDNA3.1-SOX9 group than that of NC group, and the cell formation in si-SOX9 + miR-145 inhibitor group and NC group had no significant difference. d invasion assays of two kinds of cancer cells under different interference conditions. e the scratch wound healing assays of two kinds of cancer cells under different interference conditions. **P < 0.01, compared with NC group

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Molecular Medicine

ISSN: 1528-3658