Fig. 3
From: TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis
TRIF is critical for caspase-11-dependent immune responses, organ injury and lethality in sepsis. a-b Serum IL-1α and IL-1β levels from mice of indicated genotypes were subjected to either cecum sublethal ligation and puncture (CLP) or sham operation. c H&E staining of the lungs from mice of indicated genotypes (n = 5) were subjected to either sublethal CLP or sham operation. d-e The serum alanine aminotransferase (ALT) and creatinine (Cre) levels from mice of indicated genotypes subjected to either sublethal CLP or sham operation. f Kaplan Meier survival curves for the indicated genotypes subjected to either sublethal CLP or sham operation. *P<0.05; **P<0.01; ***P<0.001 (Student’s t-test and log-rank test for survival). Graphs show the mean ± SD. Data are representative of at least three independent experiments