Fig. 6From: Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolomeGastrointestinal permeability of older adult mice to sugar probes. Gastrointestinal permeability was measured as altered ratios of sugar probes excreted in the urine. a B6 mice were treated with 5 mg aspirin two hours prior to feeding with sugar probes (open star sign, untreated n = 14; closed star sign, treated n = 6). b 10-week old or c 22-week old female B6 (closed diamond) or pIgR−/− (open diamond) mice were given an oral dose of sugar probes containing sucrose, lactulose, sucralose and mannitol. The concentration of sugar probes in urine was collected 24-h post feeding and analysed by GC-MS. Data are represented as the ratio of sugar probe concentrations within samples and the horizontal bar represents the mean of each group. Statistical analysis was performed using the Mann Whitney U-test, ns indicates p > 0.05. Data are pooled from two independently performed experimentsBack to article page