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Fig. 1 | Molecular Medicine

Fig. 1

From: PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma

Fig. 1

PGK1 expression is elevated in endometrial cancer tissues and is associated with FIGO stages and lymphatic metastasis. a. qPCR was used to detect the expression levels of PGK1 in endometrial carcinoma tissues (n = 56) and in normal human endometrial tissues (n = 20). b. qPCR was used to compare the expression levels of PGK1 in stage I/II endometrial carcinoma tissues (n = 37) and in stage III/IV endometrial carcinoma tissues (n = 19). c. qPCR was performed to examine the expression levels of PGK1 in endometrial carcinoma tissues with positive lymph node metastasis (n = 14) and with negative lymph node metastasis (n = 42). Data were shown as mean ± SD based on three independent experiments. ***, P < 0.001 compared with normal tissue; *, P < 0.05 compared with Stage I/II; **P < 0.01 compared with metastasis negative group

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Molecular Medicine

ISSN: 1528-3658