Fig. 4

Deficiency in CIRP inhibited the altered open field behavior exhibited by WT mice. a Representative heat map of WT and CIRP^−/− mice exploring the chamber. b Percent time spent exploring either the center or periphery of the chamber. c Total distance traversed during the test. d Time spent for self-grooming during the OF tasks. Data are expressed as mean ± SE; * P < 0.05; ** P < 0.005, *** P < 0.001 by t-test