|
Cohort 1
|
|
WT-baseline
|
25.2 ± 0.53
|
0.98 ± 0.21
|
209 ± 10.0
|
84.62 ± 5.87
|
16.84 ± 1.68
|
|
WT-post-alcohol
|
23.6 ± 0.43
|
0.67 ± 0.10
|
203 ± 11.9
|
82.86 ± 8.58
|
14.88 ± 1.05
|
|
WT baseline vs. post-alcohol (P value)
|
0.029
|
0.218
|
0.807
|
0.780
|
0.171
|
|
KO-baseline
|
28.6 ± 1.11
|
1.00 ± 0.20
|
212 ± 19.0
|
91.48 ± 7.82
|
18.90 ± 1.60
|
|
KO-post-alcohol
|
27.8 ± 1.23
|
0.79 ± 0.11
|
193 ± 7.80
|
108.47 ± 9.51
|
21.18 ± 2.42
|
|
KO baseline vs. KO post-alcohol (P value)
|
0.181
|
0.348
|
0.421
|
0.072
|
0.528
|
|
WT + KO (baseline)
|
27.0 ± 0.7
|
0.99 ± 0.14
|
211 ± 12.0
|
88.37 ± 4.98
|
18.08 ± 1.27
|
|
WT + KO (post-alcohol)
|
25.8 ± 0.81
|
0.73 ± 0.07
|
198 ± 6.67
|
96.28 ± 6.90
|
18.20 ± 1.52
|
|
WT + KO baseline vs WT + KO post-alcohol (P value)
|
0.009
|
0.113
|
0.403
|
0.146
|
0.991
|
|
Cohort 2
|
|
WT-baseline
|
23.60 ± 0.81
|
0.67 ± 0.04
|
184 ± 11.8
|
99.32 ± 10.86
|
16.41 ± 2.31
|
|
WT-post-saline
|
24.40 ± 0.60
|
0.83 ± 0.04
|
175 ± 14.6
|
67.07 ± 7.09
|
12.09 ± 0.55
|
|
WT baseline vs. post-saline (P value)
|
0.242
|
0.09
|
0.73
|
0.058
|
0.211
|
|
KO-baseline
|
23.0 ± 0.55
|
0.61 ± 0.04
|
190 ± 12.4
|
71.80 ± 9.29
|
12.66 ± 0.56
|
|
KO-post-saline
|
23.4 ± 0.40
|
0.66 ± 0.11
|
197 ± 9.5
|
72.57 ± 4.67
|
13.58 ± 0.72
|
|
KO baseline vs. KO post-saline (P value)
|
0.374
|
0.678
|
0.499
|
0.934
|
0.346
|
|
WT + KO (baseline)
|
23.30 ± 0.47
|
0.64 ± 0.03
|
187 ± 7.8
|
85.56 ± 8.15
|
14.53 ± 1.35
|
|
WT + KO (post-saline)
|
23.90 ± 7.56
|
0.74 ± 0.23
|
186 ± 9.0
|
69.82 ± 4.11
|
12.83 ± 4.54
|
|
WT + KO baseline vs WT + KO post-saline (P value)
|
0.111
|
0.135
|
0.377
|
0.114
|
0.322
|
