Skip to main content

Table 6 Absolute SUV values corrected for plasma glucose concentration. Global SUV values corrected for glucose levels at post-alcohol between WT and CIRP−/− mice are significant (P = 0.034, unpaired t-test). No group differences were seen in global SUV values in percent changes between pre- and post-saline treatment (P > 0.07, unpaired test)

From: Extracellular cold inducible RNA-binding protein mediates binge alcohol-induced brain hypoactivity and impaired cognition in mice

  Weight (g) Injected dose (mCi) Blood glucose (mg/dl) Global SUV Global SUV x blood glucose
Cohort 1
 WT-baseline 25.2 ± 0.53 0.98 ± 0.21 209 ± 10.0 84.62 ± 5.87 16.84 ± 1.68
 WT-post-alcohol 23.6 ± 0.43 0.67 ± 0.10 203 ± 11.9 82.86 ± 8.58 14.88 ± 1.05
 WT baseline vs. post-alcohol (P value) 0.029 0.218 0.807 0.780 0.171
 KO-baseline 28.6 ± 1.11 1.00 ± 0.20 212 ± 19.0 91.48 ± 7.82 18.90 ± 1.60
 KO-post-alcohol 27.8 ± 1.23 0.79 ± 0.11 193 ± 7.80 108.47 ± 9.51 21.18 ± 2.42
 KO baseline vs. KO post-alcohol (P value) 0.181 0.348 0.421 0.072 0.528
 WT + KO (baseline) 27.0 ± 0.7 0.99 ± 0.14 211 ± 12.0 88.37 ± 4.98 18.08 ± 1.27
 WT + KO (post-alcohol) 25.8 ± 0.81 0.73 ± 0.07 198 ± 6.67 96.28 ± 6.90 18.20 ± 1.52
 WT + KO baseline vs WT + KO post-alcohol (P value) 0.009 0.113 0.403 0.146 0.991
Cohort 2
 WT-baseline 23.60 ± 0.81 0.67 ± 0.04 184 ± 11.8 99.32 ± 10.86 16.41 ± 2.31
 WT-post-saline 24.40 ± 0.60 0.83 ± 0.04 175 ± 14.6 67.07 ± 7.09 12.09 ± 0.55
 WT baseline vs. post-saline (P value) 0.242 0.09 0.73 0.058 0.211
 KO-baseline 23.0 ± 0.55 0.61 ± 0.04 190 ± 12.4 71.80 ± 9.29 12.66 ± 0.56
 KO-post-saline 23.4 ± 0.40 0.66 ± 0.11 197 ± 9.5 72.57 ± 4.67 13.58 ± 0.72
 KO baseline vs. KO post-saline (P value) 0.374 0.678 0.499 0.934 0.346
 WT + KO (baseline) 23.30 ± 0.47 0.64 ± 0.03 187 ± 7.8 85.56 ± 8.15 14.53 ± 1.35
 WT + KO (post-saline) 23.90 ± 7.56 0.74 ± 0.23 186 ± 9.0 69.82 ± 4.11 12.83 ± 4.54
 WT + KO baseline vs WT + KO post-saline (P value) 0.111 0.135 0.377 0.114 0.322