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Fig. 1 | Molecular Medicine

Fig. 1

From: FBXW7 suppresses HMGB1-mediated innate immune signaling to attenuate hepatic inflammation and insulin resistance in a mouse model of nonalcoholic fatty liver disease

Fig. 1

FBXW7 improves NAFLD and related metabolic parameters in HFD-fed mice (n = 5). a Immunoblotting and densitometry of FBXW7 and GFP in mouse livers. b The levels of fasting blood glucose in different treatment groups. c The levels of fasting serum insulin in different treatment groups. d Serum TG levels in different treatment groups. e Hepatic TG levels in different treatment groups. f Serum ALT activities in different treatment groups. g H&E staining and Oil Red O staining of liver sections in different treatment groups. Magnification 200X. All of the values are expressed as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 versus the ND + Ad-GFP group; ###P < 0.001 versus the HFD + Ad-GFP group

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Molecular Medicine

ISSN: 1528-3658