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Fig. 2 | Molecular Medicine

Fig. 2

From: Gut microbiota promote the inflammatory response in the pathogenesis of systemic lupus erythematosus

Fig. 2

Effect of FMT from control mice and SLE mice into GF mice. (A) SourceTracker results of recipient mice (5 mice per group). The first row shows the result of each mouse in the GF + B6 group and the second row shows the result of each mouse in the GF + SLE group. (B) Significantly different species in the SLE group and C57/B6 group (11 mice per group; left); difference in mean proportions between the groups, P-values, and 95% confidence intervals (right). 16 s rRNA gene sequences were assigned to the species level based on greater than 97% identity to reference sequences (see Materials and methods). (C) Significantly different species in the GF + SLE group and the GF + B6 group (5 mice per group); difference in mean proportions between the groups, P-values, and 95% confidence intervals (right). (D)Anti-dsDNA antibody titers of mice in the GF + SLE group and the GF + B6 group (5 mice per group). Data represent one of three independent experiments, and error bars represent means ± SEMs

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