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Fig. 5 | Molecular Medicine

Fig. 5

From: An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components

Fig. 5

Prognostic relevance of the crosstalk between JAK-STAT signaling and IRF8. a Patients are grouped into four categories based on median 28-gene and IRF8 expression values. Kaplan-Meier analyses are performed on the four patient groups to determine the ability of the combined JAK-STAT-IRF8 model in determining overall survival in glioma and renal cancers. P values are obtained from log-rank tests. b Table inset shows univariate Cox proportional hazards analyses of the relationship between JAK-STAT signaling and IRF8. Significant P values are highlighted in bold. CI = confidence interval

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