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Fig. 5 | Molecular Medicine

Fig. 5

From: Inhibition of microRNA-29a alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice via upregulation of GAB1

Fig. 5

Schematic representation of miR-29a in hyperoxia-induced BPD in neonatal mice. miR-29a is highly expressed and GAB1 is lowly expressed in hyperoxia-induced BPD in neonatal mice. Downregulation of miR-29a attenuates cell apoptosis and promotes cell proliferation in lung tissues by increasing GAB1 expression, ultimately retarding the development of BPD. miR-29a, microRNA-29a; GAB1, GRB2-associated-binding protein 1; BPD, bronchopulmonary dysplasia

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Molecular Medicine

ISSN: 1528-3658