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Fig. 5 | Molecular Medicine

Fig. 5

From: NGF (−198C > T, Ala35Val) and p75NTR (Ser205Leu) gene mutations are associated with liver function in different histopathological profiles of the patients with chronic viral hepatitis in the Brazilian Amazon

Fig. 5

Association of liver function with NGF haplotypes according to hepatic inflammation. a The viral load was higher in patients with the haplotype containing the Ala+/+ variant at all stages of inflammation. b, c, d Only in A2-A3 inflammation was the level of serum markers of liver damage lower in patients with the haplotype containing the Ala+/+ variant. This trend was plotted on the heatmap grouping graph (e). Heterozygous: ArgValAlaAla - ArgValValAla. Other haplotypes: ArgValAlaAla, ArgMetAlaAla, ArgValAlaAla, ArgValValAla, ArgMetValAla, ArgMetValAla, ArgValAlaAla, and ArgValAlaAla

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Molecular Medicine

ISSN: 1528-3658