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Table 1 Characterization of stratified groups according to METAVIR classification

From: NGF (−198C > T, Ala35Val) and p75NTR (Ser205Leu) gene mutations are associated with liver function in different histopathological profiles of the patients with chronic viral hepatitis in the Brazilian Amazon

METAVIR

Genre

Populations (%)

Ethylism

Comorbidities

V.L. (log10)a

ALTa

AST*

GGTa

M

F

PHCC

PHBC

No

Yes

No

Yes

Degree of hepatic inflammation

 A0-A1

43

26

40 (58.82)

29 (82.86)

36 (72.00)

33 (66.00)

33 (78.57)

36 (59.02)

5.63 ± 0.74

62.52 ± 60.48

62.52 ± 60.48

63.19 ± 74.28

 A2-A3

19

15

28 (41.18)

06 (17.14)

14 (28.00)

17 (34.00)

9 (21.43)

25 (40.98)

5.21 ± 1.15

106.93 ± 74.84

90.23 ± 71.84

89.33 ± 60.93

Degree of liver fibrosis

 F0-F1

29

20

27 (39.71)

22 (62.86)

26 (52.00)

23 (46.00)

29 (69.05)

20 (32.79)

5.31 ± 1.00

72.53 ± 71.50

55.62 ± 40.16

66.68 ± 74.94

 F2

16

10

17 (25.00)

09 (25.71)

13 (26.00)

14 (28.00)

4 (09.52)

23 (37.70)

5.63 ± 0.64

74.88 ± 63.10

62.77 ± 47.64

62.79 ± 47.43

 F3-F4

17

11

24 (35.29)

04 (11.43)

11 (22.00)

13 (26.00)

9 (21.43)

18 (29.51)

5.43 ± 1.14

87.96 ± 69.11

82.87 ± 74.6

91.90 ± 80.45

 Total

62

41

68

35

50

50

42

61

5.45 ± 0.96

76.86 ± 68.33

64.00 ± 52.69

72.19 ± 70.75

  1. a - Mean ± standard deviation values; PHCC Patients with chronic hepatitis C, PHBC Patients with chronic hepatitis B, V.L. Viral Load