Skip to main content

Table 2 Bivariate analysis of risk factors related to inflammation and hepatic fibrosis classified according to the METAVIR scale

From: NGF (−198C > T, Ala35Val) and p75NTR (Ser205Leu) gene mutations are associated with liver function in different histopathological profiles of the patients with chronic viral hepatitis in the Brazilian Amazon

FACTORS

Degree of hepatic inflammation

   

Degree of liver fibrosis

   

A0-A1

A2-A3

P

Odds ratio

CI 95%

F0-F1

F2

F3-F4

P

Odds

ratio

CI 95%

GENDER

n (%)

n (%)

   

n (%)

n (%)

n (%)

   

 Male

43 (62.32)

19 (55.88)

0.67

  

29 (59.18)

16 (61.54)

17 (60.71)

0.98Ω

  

 Female

26 (37.68)

15 (44.12)

   

20 (40.82)

10 (38.46)

11 (39.29)

   

VL (log10) (median)

5.4109

5.3664

0.65

  

4.4402

5.6433

5.6503

< 0.05Ψ

1.97*

0.34–0.75

ALT

  ≤ 34 UI/L

26 (40.00)

1 (03.23)

< 0.01

20.00#

1.57–155.87

20 (42.55)

4 (15.38)

3 (13.04)

0.01

9.74#

1.16–81.69

  > 34 UI/L

39 (60.00)

30 (96.77)

   

27 (57.45)

22 (84.66)

20 (86.96)

   

AST

  ≤ 55 UI/L

44 (67.69)

10 (31.25)

< 0.01

4.61#

1.85–11.46

30 (62.50)

15 (57.69)

9 (30.13)

0.17

  

  > 55 UI/L

21 (32.31)

22 (68.75)

   

18 (37.50)

11 (42.31)

14 (60.87)

   

GGT

  ≤ 64 UI/L (♂)

≤36 UI/L (♀)

41 (67.21)

7 (21.88)

< 0.01

7.32#

2.71–19.78

26 (57.78)

12 (50.00)

10 (41.67)

0.44

  

  > 64 UI/L (♂)

> 36 UI/L (♀)

20 (32.79)

25 (78.12)

   

19 (42.22)

12 (50.00)

14 (58.33)

   

Ethylism

 No

36 (72.00)

14 (28.00)

0.65

  

26 (52.00)

13 (26.00)

11 (22.00)

0.83

  

 Yes

33 (66.00)

17 (34.00)

   

23 (46.00)

14 (28.00)

13 (26.00)

   

Comorbidities

 No

33 (78.57)

9 (21.43)

0.04

2.55#

1.04–6.24

29 (69.05)

4 (09.52)

9 (21.43)

< 0.01

1.63*

 Yes

36 (59.02)

25 (40.98)

   

20 (32.79)

23 (37.70)

18 (29.51)