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Fig. 2 | Molecular Medicine

Fig. 2

From: Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach

Fig. 2

Utilization of IGHV1 family genes by CBS-IG and by CLL stereotype rearrangements. Normal (s-BCS) CBS-IG rearrangements are classified as typical (grey) or non-typical (white) based upon whether the IGHV1 genes utilized were the same or different from those commonly used by CLL clones for a given rearrangement (black). The relative frequency of typical and non-typical CBS-IG in s-BCS (considered in bulk) for each stereotype subset is reported on the right of the figure. Numbers in boxes indicate the total number of sequences investigated for each subset

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