Fig. 4

Genes regulated by D2 and D3 and relative effect of differentiation alone. The numbers of significant probes are indicated in each pie chart. The top pie charts in all panels indicate the number of probes that are up- or down-regulated by vitamin D2 (a and c) or D3 (b and d) compared to the control at the same time point (a and b, 24 h; c and d, 72 h). The bottom pie charts of all panels describe how these genes are regulated by differentiation (defined by comparing Ctrl 72 h vs Ctrl 24 h). Differentially regulated genes were obtained according to the same criteria described in the legend to Fig. 2a. All the probes-genes are included in Additional File 1, where the membership of the pie chart groups is reported