Fig. 7
From: circKIF4A promotes tumorogenesis of glioma by targeting miR-139-3p to activate Wnt5a signaling
circKIF4A knockdown suppressed glioma cells tumorigenesis in nude mice. A172 and LN229 cells stably expressing sh-circKIF4A were injected into the nude mice. a Representative pictures of isolated xenografts were shown. b The tumor volume of each mouse was measured every 5 days. c 30 day later, the tumor weight of each group mouse was measured. d The expression level of circKIF4A, miR-139-3p and Wnt5a was measured by qRT-PCR. e Ki67 and Wnt5a protein level was detected by immunohistochemical staining. *p < 0.05, **p < 0.01, ***p < 0.001