Fig. 1
From: Estrogen-regulated PTTG1 promotes breast cancer progression by regulating cyclin kinase expression
The levels of PTTG1 were associated with poor survival rates in breast cancer. To analyze the relationship between PTTG1 and survival rate of patients with breast cancer, GSE22220 from the GEO dataset was applied. The dataset includes live and deceased cohorts according to the survival status of patients. The mRNA expression of PTTG1 was compared between live and deceased cohorts. a The mRNA levels of PTTG1 in survival patients and deceased patients. b The mRNA levels of PTTG1 in patients with or without lymphatic metastasis. c The mRNA levels of PTTG1 in patients with different tumor grades. d Kaplan–Meier plots were used to analyze stratification of survival rate in cancer patients according to their PTTG1 levels. Data were represented as mean ± S.D. *P < 0.05, **P < 0.01, ***P < 0.001, ns indicates no significance