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Fig. 3 | Molecular Medicine

Fig. 3

From: An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes

Fig. 3

Heatmap about the potential down-stream pathways of the SMGs. GSEA is performed to evaluation the significance of each pathway. Each cell is colored according to the transformed GSEA-based FDR value where the absolute value is equal to the –log10(FDR) and the sign represents the regulation direction (+/−, up/down regulation)

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