Skip to main content
Fig. 6 | Molecular Medicine

Fig. 6

From: An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes

Fig. 6

A core association network between SMG and down-stream elements. Yellow nodes are SMGs, the other nodes are genes showing the top-50 important scores in separating the two subtypes for LUSC, and the inflammatory relevant ones are marked by green. Edges stand for the significant associations (T-test, un-paired, two-sided, FDR adjusted P-value < 0.05), and edge colors represent the log2 transformed fold change (log2FC) values of down-stream genes in mRNA level between samples with and without mutations in the SMG

Back to article page

Molecular Medicine

ISSN: 1528-3658