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Table 4 Haplotype analysis of the IL-1B block formed by rs1143630, rs1143627, rs16944, and rs1143623, and the association with EC risk

From: IL-1B rs2853550 polymorphism contributes to esophageal cancer susceptibility in Chinese Han population of Northwest China

Haplotype Block

Frequency (Case)

Frequency (Control)

Without Adjustment

With Adjustment

OR (95% CI)

pa

OR (95% CI)

pb

GAGC

0.54

0.52

1.00

–

1

–

GGAG

0.21

0.24

0.83 (0.65–1.06)

0.130

0.99 (0.74–1.31)

0.930

TGAG

0.15

0.16

0.94 (0.72–1.24)

0.680

1.00 (0.74–1.36)

0.990

GGAC

0.09

0.07

1.19 (0.83–1.71)

0.350

1.28 (0.85–1.93)

0.240

  1. OR Odds ratio, 95% CI 95% confidence interval
  2. pa: p-values calculated by logistic regression analysis
  3. pb: p-values calculated by logistic regression analysis with adjustments for gender and age
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Molecular Medicine

ISSN: 1528-3658