Skip to main content
Fig. 7 | Molecular Medicine

Fig. 7

From: A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients

Fig. 7

Survival analysis of combinational of polymorphisms in TP53, MDM2 and P73 genes. Overall survival comparison between patient’s group and combination of SNP markers of TP53, and its associated genes. In both picture (a & b) “1” indicates to patients containing risk genotypes and “0” indicates to patients containing non risk genotypes of all three loci. a. Kaplan-Meier OS analysis of patients with risk allele containing genotypes in TP53 codon 72 (R/R, or R/P), MDM2 SNP 309 (G/G, or T/G) and P73 73 bp deletion (D/D, or I/D) loci that denoted as () vs at least two loci with non risk genotype b. Kaplan-Meier OS analysis of patients with I/I genotypes (non risk) of P73 (73 bp Indel) polymorphism in combination with risk genotypes of TP53 codon 72 (R/R, or R/P), and MDM2 SNP 309 (G/G, or T/G) loci vs all of the patients carrying at least two loci with non risk genotypes. Number of patients with respective genotypes denoted by “n” in each of the survival curves

Back to article page

Molecular Medicine

ISSN: 1528-3658