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Table 2 The correlation between the MC4R polymorphisms and the risk of obesity [n (%)]

From: The MC4R SNPs, their haplotypes and gene-environment interactions on the risk of obesity

SNP Genotype Control
(n = 978)
Obesity
(n = 858)
χ2 P Adjusted OR
(95% CI)
*P
rs17782313 T > C TT 823 (84.2) 633 (73.8) 29.974 <  0.001 1
CT+ CC 155 (15.8) 225 (26.2)    1.428 (1.066–2.061) 0.019
MAF 163 (8.3) 237 (13.8) 28.258 <  0.001   
PHWE 0.613 0.210     
rs476828 T > C TT 780 (79.8) 582 (67.8) 33.921 <  0.001 1
CT+ CC 198 (20.2) 276 (32.2)    1.585 (1.176–2.136) 0.003
MAF 213 (10.9) 293 (17.1) 29.431 <  0.001   
PHWE 0.262 0.053     
rs12970134 G > A GG 765 (78.2) 606 (70.6) 13.927 <  0.001 1
AG+ AA 213 (21.8) 252 (29.4)    1.253 (0.924–1.698) 0.147
MAF 224 (11.5) 266 (15.5) 12.961 <  0.001   
PHWE 0.565 0.085     
  1. MC4R The melanocortin 4 receptor gene, MAF Minor allele frequency, HWE Hardy-Weinberg equilibrium. P was detected as Chi-square test probability. *P was determined as Logistic test probability