Skip to main content
Fig. 2 | Molecular Medicine

Fig. 2

From: SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model

Fig. 2

PHPS1 treatment decreased kidney/body weight index (KI) elevated by Hem/CLP. The kidneys were collected 24 h post Hem/CLP or Sham operation. Vehicle treated Hem/CLP mice showed increased KI compared to Shams and PHPS1 treated Hem/CLP mice. *, P < 0.05, versus Sham (S/S); #, P < 0.05, PHPS1 treated group (Hem/CLP + PHPS1) versus Hem/CLP + vehicle (Hem/CLP). One-way ANOVA and a Student-Newman-Keuls’ test, Mean ± SD; n = 6 mice/group

Back to article page

Molecular Medicine

ISSN: 1528-3658